NeuroStage · Surgical Planning on Apple Vision Pro

Brain tumor surgical planning in immersive 3D on Apple Vision Pro

Automated brain tumor segmentation powered by OncoAI, delivered as surgeon-ready 3D models — walk around the tumor in true stereoscopic space, straight from a DICOM upload.

NeuroStage brain tumor segmentation — enhancing tumor, non-enhancing core, and peritumoral edema overlaid on a coronal MRI slice

Research Preview — not FDA cleared. For research and surgical-planning rehearsal only; not for clinical diagnosis or intraoperative guidance.

The clinical gap

Surgeons think in 3D. The review is still slice-by-slice.

Brain tumor planning is three-dimensional reasoning — lesion morphology, eloquent-area proximity, approach trajectory. Yet pre-operative review is still conducted slice-by-slice on 2D MRI, leaving the surgeon’s mental 3D reconstruction as the rate-limiting step. Existing 3D tools demand manual segmentation, desktop-only workflows, or single-user review.

NeuroStage closes the gap by pairing Carina’s automated brain tumor segmentation with an immersive spatial viewer — delivering surgeon-ready 3D models directly from a DICOM upload.

How it works

DICOM in, surgeon-ready 3D out

NeuroStage is the clinical-frontend tier of Carina’s brain-imaging pipeline: upload a study from the web, OncoAI runs the analysis, and the result is available immediately in both the web browser and the spatial viewer — no manual segmentation step.

NeuroStage three-stage flow: 01 Upload a DICOM study from the web; 02 Analyze with OncoAI — co-registration, resampling, multi-class tumor segmentation; 03 Review in the Apple Vision Pro spatial viewer

Automated segmentation

Multi-class tumor labels, no manual contouring

OncoAI co-registers the MRI contrasts to a common 1×1×1 mm grid and produces a multi-class label — enhancing tumor, non-enhancing core, and peritumoral edema — that drives both the 2D overlay and the 3D surfaces the surgeon reviews.

Four panels from the demo study: T1c, FLAIR, OncoAI segmentation overlay (enhancing tumor, non-enhancing core, peritumoral edema), and 3D tumor surfaces
From the bundled BraTS demo study, rendered with the viewer’s own label colors. T1c · FLAIR · segmentation overlay · 3D tumor surfaces.

Key capabilities

From upload to immersive review, in one platform

Immersive viewer on Apple Vision Pro

True-stereoscopic tumor surfaces with hand-driven slice-plane manipulation — reviewed at scale in the surgeon’s own space. Meta Quest 3 support is under evaluation.

Automated tumor segmentation

OncoAI’s brain tumor model produces multi-class labels — enhancing tumor, non-enhancing core, peritumoral edema — with no manual contouring.

Multi-contrast MRI review

T1, T1c, T2, and FLAIR co-registered to a common space, with on-the-fly contrast switching on the same slice geometry.

Web study management

Institution-scoped study list, secure DICOM upload and download, role-based access, and 2FA — from any authorized browser.

Institutional data control

On-premise or HIPAA-eligible cloud deployment. Integrates with CuratAI for PACS curation and de-identification upstream.

One canonical output

Every study resolves to co-registered NIfTI volumes plus a tumor label — browsed from the web, opened in the spatial viewer, no per-site install.

The management surface

Upload, track, and share — from any authorized browser

Study-centric, institution-scoped

  • Drag-and-drop DICOM upload; patient and study metadata read straight from the headers.
  • Searchable study list with per-study analysis status and secure download.
  • Three roles — staff, institution admin, institution user — with 2FA. Everything scoped to the institution.
NeuroStage web study list — searchable table of studies with patient, ID, study date, and per-study analysis status, plus a drag-and-drop DICOM upload zone

Integrated with the Carina platform

One platform, from PACS to the operating plan

NeuroStage is the surgeon-facing surface of a pipeline that starts at the PACS. It inherits Carina’s deployment, security, and regulatory infrastructure — the same stack behind two FDA-cleared products.

Carina platform flow: CuratAI (data curation) to OncoAI (oncology segmentation) to NeuroStage (clinical frontend) to the neurosurgeon, with QuantBrain alongside on the same brain-imaging stack

Deployment

Two surfaces, one study

Web

Study upload, status, management, and lightweight review — any modern browser.

Spatial viewer

Immersive 3D review and surgical rehearsal — Apple Vision Pro (Meta Quest 3 under evaluation).

Where it runs

Carina’s standard server stack, with optional on-premise deployment for data-residency requirements.

Status

Research Preview

Research Preview — not FDA cleared. NeuroStage is available to selected academic medical centers under early-access agreements for research and surgical-planning rehearsal. It is not intended for clinical diagnosis or intraoperative guidance. Clinical validation work is underway.

Open an early-access partnership

For academic neurosurgery departments exploring surgical-planning rehearsal and neurosurgical training.